CLC (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CLC partial ORF ( NP_001819.2, 52 a.a. - 142 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FHFQVCFGRRVVMNSREYGAWKQQVESKNMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSYLKR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.75
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CLC
Entrez GeneID
1178GeneBank Accession#
NM_001828Protein Accession#
NP_001819.2Gene Name
CLC
Gene Alias
LGALS10, LPPL_HUMAN, MGC149659
Gene Description
Charcot-Leyden crystal protein
Omim ID
153310Gene Ontology
HyperlinkGene Summary
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq
Other Designations
Charot-Leyden crystal protein|eosinophil lysophospholipase|galactin-10|galectin 10|lysolecithin acylhydrolase
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Interactome
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Disease
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