AP1S1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human AP1S1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human AP1S1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human AP1S1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — AP1S1
Entrez GeneID
1174GeneBank Accession#
AP1S1Gene Name
AP1S1
Gene Alias
AP19, CLAPS1, FLJ92436, SIGMA1A, WUGSC:H_DJ0747G18.2
Gene Description
adaptor-related protein complex 1, sigma 1 subunit
Omim ID
603531Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq
Other Designations
AP-1 complex subunit sigma-1A|HA1 19 kDa subunit|clathrin assembly protein complex 1 sigma-1A small chain|clathrin coat assembly protein AP19|clathrin-associated/assembly/adaptor protein, small 1 (19kD)|golgi adaptor HA1/AP1 adaptin sigma-1A subunit|sigma
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Interactome
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Pathway
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