AP2M1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human AP2M1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human AP2M1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human AP2M1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — AP2M1
Entrez GeneID
1173GeneBank Accession#
AP2M1Gene Name
AP2M1
Gene Alias
AP50, CLAPM1, mu2
Gene Description
adaptor-related protein complex 2, mu 1 subunit
Omim ID
601024Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
AP-2 mu 2 chain|HA2 50 kDA subunit|clathrin adaptor complex AP2, mu subunit|clathrin assembly protein complex 2 medium chain|clathrin coat adaptor protein AP50|clathrin-associated/assembly/adaptor protein, medium 1|plasma membrane adaptor AP-2 50kDA prote
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