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AP2M1 rabbit monoclonal antibody

  • Catalog # : H00001173-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human AP2M1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human AP2M1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human AP2M1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1173
  • GeneBank Accession#:
  • AP2M1
  • Gene Name:
  • AP2M1
  • Gene Alias:
  • AP50,CLAPM1,mu2
  • Gene Description:
  • adaptor-related protein complex 2, mu 1 subunit
  • Gene Summary:
  • This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • AP-2 mu 2 chain,HA2 50 kDA subunit,clathrin adaptor complex AP2, mu subunit,clathrin assembly protein complex 2 medium chain,clathrin coat adaptor protein AP50,clathrin-associated/assembly/adaptor protein, medium 1,plasma membrane adaptor AP-2 50kDA prote
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