CHRNE (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CHRNE partial ORF ( NP_000071, 21 a.a. - 130 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KNEELRLYHHLFNNYDPGSRPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFGGIETLRVPSELVWLPEIVLENNIDGQFGVAYDANVLV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (88); Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CHRNE
Entrez GeneID
1145GeneBank Accession#
NM_000080Protein Accession#
NP_000071Gene Name
CHRNE
Gene Alias
ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS
Gene Description
cholinergic receptor, nicotinic, epsilon
Gene Ontology
HyperlinkGene Summary
Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq
Other Designations
AchR epsilon subunit|cholinergic receptor, nicotinic, epsilon polypeptide|nicotinic acetylcholine receptor epsilon polypeptide
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Interactome
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Disease
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