CHRND monoclonal antibody (M01), clone 2B2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CHRND.
Immunogen
CHRND (NP_000742, 24 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EEERLIRHLFQEKGYNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGNISVLRLPPDMVWLPEIVLENNNDGSFQISYSCN
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.51 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CHRND expression in transfected 293T cell line by CHRND monoclonal antibody (M01), clone 2B2.
Lane 1: CHRND transfected lysate (Predicted MW: 58.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CHRND is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — CHRND
Entrez GeneID
1144GeneBank Accession#
NM_000751Protein Accession#
NP_000742Gene Name
CHRND
Gene Alias
ACHRD, CMS2A, FCCMS, SCCMS
Gene Description
cholinergic receptor, nicotinic, delta
Gene Ontology
HyperlinkGene Summary
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [provided by RefSeq
Other Designations
cholinergic receptor, nicotinic, delta polypeptide|nicotinic acetylcholine receptor delta polypeptide
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Interactome
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Disease
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