CHRNB1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CHRNB1 partial ORF ( NP_000738, 24 a.a. - 128 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SEAEGRLREKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.29
Interspecies Antigen Sequence
Mouse (93); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CHRNB1
Entrez GeneID
1140GeneBank Accession#
NM_000747Protein Accession#
NP_000738Gene Name
CHRNB1
Gene Alias
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Gene Description
cholinergic receptor, nicotinic, beta 1 (muscle)
Gene Ontology
HyperlinkGene Summary
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq
Other Designations
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)|nicotinic acetylcholine receptor beta 1 subunit
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Interactome
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Disease
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