CHRNB1 monoclonal antibody (M01), clone 4G4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CHRNB1.
Immunogen
CHRNB1 (NP_000738, 24 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SEAEGRLREKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (90)
Isotype
IgG3 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.29 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CHRNB1
Entrez GeneID
1140GeneBank Accession#
NM_000747Protein Accession#
NP_000738Gene Name
CHRNB1
Gene Alias
ACHRB, CHRNB, CMS1D, CMS2A, SCCMS
Gene Description
cholinergic receptor, nicotinic, beta 1 (muscle)
Gene Ontology
HyperlinkGene Summary
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq
Other Designations
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)|nicotinic acetylcholine receptor beta 1 subunit
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Interactome
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Disease
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