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CHRNA5 rabbit monoclonal antibody

  • Catalog # : H00001138-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CHRNA5 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CHRNA5 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CHRNA5 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1138
  • Gene Name:
  • CHRNA5
  • Gene Alias:
  • LNCR2
  • Gene Description:
  • cholinergic receptor, nicotinic, alpha 5
  • Gene Summary:
  • Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. See MIM 118508 for additional background information on AChRs.[supplied by OMIM
  • Other Designations:
  • Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5,cholinergic receptor, nicotinic, alpha polypeptide 5,neuronal nicotinic acetylcholine receptor, alpha5 subunit
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