CHRNA1 monoclonal antibody (M04), clone 2G5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CHRNA1.
Immunogen
CHRNA1 (NP_000070.1, 146 a.a. ~ 231 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CHRNA1 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — CHRNA1
Entrez GeneID
1134GeneBank Accession#
NM_000079Protein Accession#
NP_000070.1Gene Name
CHRNA1
Gene Alias
ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
Gene Description
cholinergic receptor, nicotinic, alpha 1 (muscle)
Gene Ontology
HyperlinkGene Summary
The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)|nicotinic acetylcholine receptor alpha subunit|nicotinic cholinergic receptor alpha 1
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Interactome
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Disease
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