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CHRNA1 rabbit monoclonal antibody

  • Catalog # : H00001134-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CHRNA1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CHRNA1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CHRNA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1134
  • Gene Name:
  • CHRNA1
  • Gene Alias:
  • ACHRA,ACHRD,CHRNA,CMS2A,FCCMS,SCCMS
  • Gene Description:
  • cholinergic receptor, nicotinic, alpha 1 (muscle)
  • Gene Summary:
  • The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle),nicotinic acetylcholine receptor alpha subunit,nicotinic cholinergic receptor alpha 1
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