CHN1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CHN1 full-length ORF ( NP_001813.1, 1 a.a. - 459 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
79.6
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CHN1
Entrez GeneID
1123GeneBank Accession#
NM_001822.3Protein Accession#
NP_001813.1Gene Name
CHN1
Gene Alias
ARHGAP2, CHN, DURS2, RHOGAP2
Gene Description
chimerin (chimaerin) 1
Omim ID
118423Gene Ontology
HyperlinkGene Summary
This gene encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane's retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
A-chimaerin|Chimerin 1 (GTPase-activating protein, rho, 2)|Rho GTPase-activating protein 2|a2-chimaerin|alpha-chimerin|n-chimerin
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Interactome
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Disease
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