CHN1 MaxPab mouse polyclonal antibody (B01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CHN1 protein.
Immunogen
CHN1 (NP_001813, 1 a.a. ~ 459 a.a) full-length human protein.
Sequence
MALTLFDTDEYRPPVWKSYLYQLQQEAPHPRRITCTCEVENRPKYYGREFHGMISREAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYIAKMTINPIYEHVGYTTLNREPAYKKHMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEKIHNFKVHTFRGPHWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKPDLKHVKKVYSCDLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CHN1 expression in transfected 293T cell line (H00001123-T01) by CHN1 MaxPab polyclonal antibody.
Lane 1: CHN1 transfected lysate(50.49 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CHN1
Entrez GeneID
1123GeneBank Accession#
NM_001822Protein Accession#
NP_001813Gene Name
CHN1
Gene Alias
ARHGAP2, CHN, DURS2, RHOGAP2
Gene Description
chimerin (chimaerin) 1
Omim ID
118423Gene Ontology
HyperlinkGene Summary
This gene encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding. Heterozygous missense mutations in this gene cause Duane's retraction syndrome 2 (DURS2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
A-chimaerin|Chimerin 1 (GTPase-activating protein, rho, 2)|Rho GTPase-activating protein 2|a2-chimaerin|alpha-chimerin|n-chimerin
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Interactome
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Disease
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