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CHM Pre-design Chimera RNAi

  • Catalog # : H00001121-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens choroideremia (Rab escort protein 1) (CHM), transcript variant 2950156, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001037312
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1121
  • Gene Name:
  • CHM
  • Gene Alias:
  • DXS540,FLJ38564,GGTA,HSD-32,MGC102710,REP-1,TCD
  • Gene Description:
  • choroideremia (Rab escort protein 1)
  • Gene Summary:
  • This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternative splicing results in multiple transcript variants encoding different isoforms
  • Other Designations:
  • OTTHUMP00000023628,REP-1, Rab escort protein 1,choroideremia
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