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Last updated: 2017/8/13

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CHIT1 rabbit monoclonal antibody

  • Catalog # : H00001118-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CHIT1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CHIT1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CHIT1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1118
  • GeneBank Accession#:
  • CHIT1
  • Gene Name:
  • CHIT1
  • Gene Alias:
  • CHI3,CHIT,FLJ00314,MGC125322
  • Gene Description:
  • chitinase 1 (chitotriosidase)
  • Gene Summary:
  • Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq
  • Other Designations:
  • chitotriosidase,plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
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