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AKR1C4 (Human) IP-WB Antibody Pair

  • Catalog # : H00001109-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00001109-PW1
    Immunoprecipitation of AKR1C4 transfected lysate using rabbit polyclonal anti-AKR1C4 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-AKR1C4.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-AKR1C4 (300 ul)
    2. Antibody pair for WB: mouse polyclonal anti-AKR1C4 (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1109
  • Gene Name:
  • AKR1C4
  • Gene Alias:
  • 3-alpha-HSD,C11,CDR,CHDR,DD4,HAKRA,MGC22581
  • Gene Description:
  • aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
  • Gene Summary:
  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
  • Other Designations:
  • 3 alpha-hydroxysteroid dehydrogenase/dihydrodiol dehydrogenase 4,OTTHUMP00000018997,aldo-keto reductase family 1, member C4,chlordecone reductase,dihydrodiol dehydrogenase 4,dihydrodiol dehydrogenase isozyme DD4,type I 3-alpha-hydroxysteroid dehydrogenase
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