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CTSC 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001075-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-CTSC full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 51.8
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-CTSC antibody (H00001075-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001075-T01
    CTSC transfected lysate.
    Western Blot
    QC Testing of H00001075-T01
    Lane 1: CTSC transfected lysate ( 51.8 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1075
  • Gene Name:
  • CTSC
  • Gene Alias:
  • Gene Description:
  • cathepsin C
  • Gene Summary:
  • The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • cathepsin J,dipeptidyl transferase,dipeptidyl-peptidase I
  • Gene Pathway
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