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Last updated: 2016/10/23
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CTSC purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00001075-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human CTSC protein.
  • Immunogen:
  • CTSC (NP_001805, 1 a.a. ~ 463 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of CTSC expression in transfected 293T cell line (H00001075-T01) by CTSC MaxPab polyclonal antibody.

    Lane 1: CTSC transfected lysate(50.93 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1075
  • Gene Name:
  • CTSC
  • Gene Alias:
  • Gene Description:
  • cathepsin C
  • Gene Summary:
  • The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • cathepsin J,dipeptidyl transferase,dipeptidyl-peptidase I
  • Gene Pathway
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