CETN2 monoclonal antibody (M01), clone 3F8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CETN2.
Immunogen
CETN2 (NP_004335, 85 a.a. ~ 172 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.42 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CETN2 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — CETN2
Entrez GeneID
1069GeneBank Accession#
NM_004344Protein Accession#
NP_004335Gene Name
CETN2
Gene Alias
CALT, CEN2
Gene Description
centrin, EF-hand protein, 2
Omim ID
300006Gene Ontology
HyperlinkGene Summary
Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq
Other Designations
OTTHUMP00000026058|caltractin|caltractin (20kD calcium-binding protein)
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Interactome
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Pathway
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Publication Reference
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CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response.
Barr AR, Kilmartin JV, Gergely F.
The Journal of Cell Biology 2010 Apr; 189(1):23.
Application:IF, Chicken, DT40 cells.
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CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response.
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