CETN1 monoclonal antibody (M05), clone 4C12
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant CETN1.
Immunogen
CETN1 (AAH29515.1, 16 a.a. ~ 94 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KRKVAPKPELTEDQKQEVREAFDLFDVDGSGTIDAKELKVAMRALGFEPRKEEMKKMISEVDREGTGKISFNDFLAVMT
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.32 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CETN1 expression in transfected 293T cell line by CETN1 monoclonal antibody (M05), clone 4C12.
Lane 1: CETN1 transfected lysate(19.6 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — CETN1
Entrez GeneID
1068GeneBank Accession#
BC029515Protein Accession#
AAH29515.1Gene Name
CETN1
Gene Alias
CEN1, CETN
Gene Description
centrin, EF-hand protein, 1
Omim ID
603187Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq
Other Designations
Centrin-1|EF-hand protein|calcium binding protein|centrin 1
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Interactomes
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Publication Reference
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Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.
Jiao R, Allen KJH, Malo ME, Helal M, Jiang Z, Smart K, Buhl SV, Rickles D, Bryan RA, Dadachova E.
Cancer Medicine 2019 Sep; 8(11):5289.
Application:IHC-P, Human, Human pancreatic cancer.
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Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer.
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