CES1 purified MaxPab rabbit polyclonal antibody (D01P)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CES1 protein.
Immunogen
CES1 (AAH12418.1, 1 a.a. ~ 566 a.a) full-length human protein.
Sequence
MWLPALVLATLAASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CES1 MaxPab rabbit polyclonal antibody. Western Blot analysis of CES1 expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of CES1 expression in transfected 293T cell line (H00001066-T01) by CES1 MaxPab polyclonal antibody.
Lane 1: CES1 transfected lysate(62.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CES1
Entrez GeneID
1066GeneBank Accession#
BC012418.1Protein Accession#
AAH12418.1Gene Name
CES1
Gene Alias
ACAT, CEH, CES2, HMSE, HMSE1, MGC117365, PCE-1, SES1, TGH
Gene Description
carboxylesterase 1 (monocyte/macrophage serine esterase 1)
Omim ID
114835Gene Ontology
HyperlinkGene Summary
Carboxylesterase 1 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds. Carboxylesterase deficiency may be associated with non-Hodgkin lymphoma or B-cell lymphocytic leukemia. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Other Designations
acyl coenzyme A:cholesterol acyltransferase|carboxylesterase 1|carboxylesterase 2 (liver)|cholesteryl ester hydrolase|egasyn|liver carboxylesterase|triacylglycerol hydrolase
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Interactome
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Pathway
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Disease
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