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CENPB (Human) IP-WB Antibody Pair

  • Catalog # : H00001059-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00001059-PW1
    Immunoprecipitation of CENPB transfected lysate using rabbit polyclonal anti-CENPB and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CENPB.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-CENPB (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-CENPB (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1059
  • Gene Name:
  • CENPB
  • Gene Alias:
  • -
  • Gene Description:
  • centromere protein B, 80kDa
  • Gene Summary:
  • This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000030132,centromere autoantigen B,centromere protein B,centromere protein B (80kD)
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