CENPA monoclonal antibody (M01), clone 1D4-1A3
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant CENPA.
Immunogen
CENPA (AAH00881, 1 a.a. ~ 114 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGPRRRSRKPEAPRRRSPSPTPTPGPSRRGPSLGASSHQHSRRRQGWLKEIRKLQKSTHLLIRKLPFSRLAAEAFLVHLFEDAYLLTLHAGRVTLFPKDVQLARRIRGLEEGLG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (56); Rat (56)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CENPA is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — CENPA
Entrez GeneID
1058GeneBank Accession#
BC000881Protein Accession#
AAH00881Gene Name
CENPA
Gene Alias
CENP-A
Gene Description
centromere protein A
Omim ID
117139Gene Ontology
HyperlinkGene Summary
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000122589|centromere protein A, 17kDa
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