CDKN3 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CDKN3 partial ORF ( NP_005183, 51 a.a. - 140 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
CKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.64
Interspecies Antigen Sequence
Mouse (89)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CDKN3
Entrez GeneID
1033GeneBank Accession#
NM_005192Protein Accession#
NP_005183Gene Name
CDKN3
Gene Alias
CDI1, CIP2, FLJ25787, KAP, KAP1, MGC70625
Gene Description
cyclin-dependent kinase inhibitor 3
Omim ID
123832Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CDK2-associated dual specificity phosphatase|Cdk-associated protein phosphatase|cyclin-dependent kinase interacting protein 2|cyclin-dependent kinase interactor 1|kinase-associated phosphatase
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Interactome
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Disease
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