CDKN3 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CDKN3 protein.
Immunogen
CDKN3 (NP_005183.2, 1 a.a. ~ 212 a.a) full-length human protein.
Sequence
MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEFRDKLAAHLSSRDSQSRSVSR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CDKN3 expression in transfected 293T cell line (H00001033-T01) by CDKN3 MaxPab polyclonal antibody.
Lane 1: CDKN3 transfected lysate(23.32 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to CDKN3 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — CDKN3
Entrez GeneID
1033GeneBank Accession#
NM_005192Protein Accession#
NP_005183.2Gene Name
CDKN3
Gene Alias
CDI1, CIP2, FLJ25787, KAP, KAP1, MGC70625
Gene Description
cyclin-dependent kinase inhibitor 3
Omim ID
123832Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CDK2-associated dual specificity phosphatase|Cdk-associated protein phosphatase|cyclin-dependent kinase interacting protein 2|cyclin-dependent kinase interactor 1|kinase-associated phosphatase
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Interactome
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Disease
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