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CDKN2B 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001030-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-CDKN2B full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 15.29
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-CDKN2B antibody (H00001030-B02) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001030-T01
    CDKN2B transfected lysate.
    Western Blot
    QC Testing of H00001030-T01
    Lane 1: CDKN2B transfected lysate ( 15.29 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1030
  • Gene Name:
  • CDKN2B
  • Gene Alias:
  • CDK4I,INK4B,MTS2,P15,TP15,p15INK4b
  • Gene Description:
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
  • Gene Summary:
  • This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
  • Other Designations:
  • CDK inhibitory protein,CDK4B inhibitor,OTTHUMP00000021154,OTTHUMP00000021155,cyclin-dependent kinase 4 inhibitor B,cyclin-dependent kinase inhibitor 2B,cyclin-dependent kinases 4 and 6 binding protein,multiple tumor suppressor 2,p14_CDK inhibitor,p14_INK4
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