Product Browser

Last updated: 2017/2/26

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

CDKN1A 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00001026-T03
  • Visit Frequency :
  • Countries :
  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-CDKN1A full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 18.1
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-CDKN1A antibody (H00001026-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00001026-T03
    CDKN1A transfected lysate.
    Western Blot
    QC Testing of H00001026-T03
    Lane 1: CDKN1A transfected lysate ( 18.10 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 1026
  • Gene Name:
  • CDKN1A
  • Gene Alias:
  • CAP20,CDKN1,CIP1,MDA-6,P21,SDI1,WAF1,p21CIP1
  • Gene Description:
  • cyclin-dependent kinase inhibitor 1A (p21, Cip1)
  • Gene Summary:
  • This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and may be instrumental in the execution of apoptosis following caspase activation. Two alternatively spliced variants, which encode an identical protein, have been reported. [provided by RefSeq
  • Other Designations:
  • CDK-interaction protein 1,DNA synthesis inhibitor,OTTHUMP00000016298,cyclin-dependent kinase inhibitor 1A,melanoma differentiation associated protein 6,wild-type p53-activated fragment 1
  • Interactome
  • Interactome
  • RSS
  • YouTube
  • Linkedin
  • Facebook