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Last updated: 2017/4/30
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CDK8 polyclonal antibody (A01)

  • Catalog # : H00001024-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant CDK8.
  • Immunogen:
  • CDK8 (NP_001251, 375 a.a. ~ 464 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • QQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00001024-A01
    Western Blot detection against Immunogen (35.9 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1024
  • Gene Name:
  • CDK8
  • Gene Alias:
  • K35,MGC126074,MGC126075
  • Gene Description:
  • cyclin-dependent kinase 8
  • Gene Summary:
  • The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq
  • Other Designations:
  • CDK8 protein kinase,OTTHUMP00000018158,cell division protein kinase 8,protein kinase K35
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