CDH12 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CDH12 full-length
Host
Human
Theoretical MW (kDa)
87.45
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CDH12 antibody (H00001010-B01) by Western Blots.
SDS-PAGE Gel
CDH12 transfected lysate.
Western Blot
Lane 1: CDH12 transfected lysate ( 87.45 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CDH12
Entrez GeneID
1010GeneBank Accession#
NM_004061.2Protein Accession#
NP_004052.2Gene Name
CDH12
Gene Alias
CDHB, FLJ34857
Gene Description
cadherin 12, type 2 (N-cadherin 2)
Omim ID
600562Gene Ontology
HyperlinkGene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [provided by RefSeq
Other Designations
Br-cadherin|N-cadherin 2|OTTHUMP00000115709|brain-cadherin|cadherin 12, type 2|cadherin, neural type, 2|cadherin-12|neuronal cadherin 2
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Interactome
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Disease
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