CDH11 monoclonal antibody (M02), clone 1H1
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More Files
- More Functions
Western Blot (Tissue lysate)
CDH11 monoclonal antibody (M02), clone 1H1. Western Blot analysis of CDH11 expression in human ovarian cancer.
Western Blot (Tissue lysate)
CDH11 monoclonal antibody (M02), clone 1H1. Western Blot analysis of CDH11 expression in human kidney.
Immunofluorescence (Circulating Tumor Cell)
PC3-MM2 cells were stained with CDH11-FITC labeled monoclonal antibody (Green). The cell nucleus were counterstained with DAPI (Blue).
Immunofluorescence
Immunofluorescence of monoclonal antibody to CDH11 on PC3-MM2 cell. [antibody concentration 10 ug/ml]
Western Blot detection against CHD11-His tag (61.49 KDa).
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CDH11.
Immunogen
CDH11 (P55287, 54 a.a. ~ 612 a.a) partial recombinant protein with Fc tag at C terminal. MW of the Fc tag alone is 50 KDa.
Sequence
GWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVMITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKDTVTVKIAVEDADEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNAEAYILN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (98)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against CHD11-His tag (61.49 KDa).
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CDH11 monoclonal antibody (M02), clone 1H1. Western Blot analysis of CDH11 expression in human ovarian cancer.Western Blot (Tissue lysate)
CDH11 monoclonal antibody (M02), clone 1H1. Western Blot analysis of CDH11 expression in human kidney.Western Blot (Recombinant protein)
ELISA
Immunofluorescence (Circulating Tumor Cell)
PC3-MM2 cells were stained with CDH11-FITC labeled monoclonal antibody (Green). The cell nucleus were counterstained with DAPI (Blue).Immunofluorescence
Immunofluorescence of monoclonal antibody to CDH11 on PC3-MM2 cell. [antibody concentration 10 ug/ml] -
Gene Info — CDH11
Entrez GeneID
1009GeneBank Accession#
BC013609.1Protein Accession#
P55287Gene Name
CDH11
Gene Alias
CAD11, CDHOB, OB, OSF-4
Gene Description
cadherin 11, type 2, OB-cadherin (osteoblast)
Omim ID
600023Gene Ontology
HyperlinkGene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq
Other Designations
OB-cadherin|cadherin 11, type 2|cadherin-11|osteoblast cadherin
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Interactome
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Disease
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