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CDC27 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00000996-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human CDC27 protein.
  • Immunogen:
  • CDC27 (ABM87026.1, 1 a.a. ~ 830 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of CDC27 expression in transfected 293T cell line (H00000996-T01) by CDC27 MaxPab polyclonal antibody.

    Lane 1: CDC27 transfected lysate(91.3 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 996
  • Gene Name:
  • CDC27
  • Gene Alias:
  • APC3,CDC27Hs,D0S1430E,D17S978E,HNUC
  • Gene Description:
  • cell division cycle 27 homolog (S. cerevisiae)
  • Gene Summary:
  • The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • anaphase-promoting complex, protein 3,cell division cycle protein 27,nuc2 homolog
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