CDA (Human) Recombinant Protein (P01)
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Specification
Product Description
Human CDA full-length ORF ( AAH54036, 1 a.a. - 146 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAQKRPACTLKPECVQQLLVCSQEAKQSAYCPYSHFPVGAALLTQEGRIFKGCNIENACYPLGICAERTAIQKAVSEGYKDFRAIAIASDMQDDFISPCGACRQVMREFGTNWPVYMTKPDGTYIVMTVQELLPSSFGPEDLQKTQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
41.8
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CDA
Entrez GeneID
978GeneBank Accession#
BC054036Protein Accession#
AAH54036Gene Name
CDA
Gene Alias
CDD
Gene Description
cytidine deaminase
Omim ID
123920Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq
Other Designations
OTTHUMP00000002883|cytidine aminohydrolase|cytosine nucleoside deaminase|small cytidine deaminase
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Interactome
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Disease
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