Products

Antibody Production

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

CD151

Gene Alias

GP27, MER2, PETA-3, RAPH, SFA1, TSPAN24

Gene Description

CD151 molecule (Raph blood group)

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq

Other Designations

CD151 antigen|CD151 antigen (Raph blood group)|OTTHUMP00000164434|hemidesmosomal tetraspanin CD151|membrane glycoprotein SFA-1|platelet surface glycoprotein gp27|platelet-endothelial cell tetraspan antigen 3