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CD97 Validated Chimera RNAi

  • Catalog # : H00000976-R01V
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens CD97 antigen (CD97), transcript variant 3, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001025160
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of CD97 over-expressed 293 cell line, cotransfected with CD97 Validated Chimera RNAi ( Cat # H00000976-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with CD97 monoclonal antibody (M01), clone 5D5 (Cat # H00000976-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
  • PDF DownloadProtocol Download
  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Entrez GeneID:
  • 976
  • Gene Name:
  • CD97
  • Gene Alias:
  • TM7LN1
  • Gene Description:
  • CD97 molecule
  • Gene Summary:
  • This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene cluster on the short arm of chromosome 19. The encoded product is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. The protein has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation. Alternative splicing has been observed for this gene and three variants have been found. [provided by RefSeq
  • Other Designations:
  • CD97 antigen,leukocyte antigen CD97,seven transmembrane helix receptor,seven-span transmembrane protein,seven-transmembrane, heterodimeric receptor associated with inflammation
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