TNFSF8 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: TNFSF8 transfected lysate ( 26 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
TNFSF8 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFSF8 full-length
Host
Human
Theoretical MW (kDa)
25.85
Interspecies Antigen Sequence
Mouse (70)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFSF8 antibody (H00000944-B01) by Western Blots.
Western Blot
Lane 1: TNFSF8 transfected lysate ( 26 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
TNFSF8 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TNFSF8
Entrez GeneID
944GeneBank Accession#
NM_001244Protein Accession#
NP_001235Gene Name
TNFSF8
Gene Alias
CD153, CD30L, CD30LG, MGC138144
Gene Description
tumor necrosis factor (ligand) superfamily, member 8
Omim ID
603875Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. [provided by RefSeq
Other Designations
CD153 antigen|CD30 antigen ligand|CD30 ligand|OTTHUMP00000022762
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Interactome
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