CD86 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CD86 full-length
Host
Human
Theoretical MW (kDa)
37.7
Interspecies Antigen Sequence
Mouse (50); Rat (57)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CD86 antibody (H00000942-B01) by Western Blots.
SDS-PAGE Gel
CD86 transfected lysate.
Western Blot
Lane 1: CD86 transfected lysate ( 37.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CD86
Entrez GeneID
942GeneBank Accession#
BC040261.1Protein Accession#
-Gene Name
CD86
Gene Alias
B7-2, B70, CD28LG2, LAB72, MGC34413
Gene Description
CD86 molecule
Omim ID
601020Gene Ontology
HyperlinkGene Summary
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq
Other Designations
B-lymphocyte activation antigen B7-2|B7-2 antigen|CD28 antigen ligand 2|CD86 antigen|CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)|CTLA-4 counter-receptor B7.2
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Interactome
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Disease
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