MS4A1 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human MS4A1 full-length ORF ( AAH02807, 1 a.a. - 297 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
58.41
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MS4A1
Entrez GeneID
931GeneBank Accession#
BC002807Protein Accession#
AAH02807Gene Name
MS4A1
Gene Alias
B1, Bp35, CD20, LEU-16, MGC3969, MS4A2, S7
Gene Description
membrane-spanning 4-domains, subfamily A, member 1
Omim ID
112210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq
Other Designations
B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Isolation and characterization of human anti-CD20 single-chain variable fragment (scFv) from a Naive human scFv library.
Nasir Shams, Shahryar Khoshtinat Nikkhoi, Zhanjun Gu, Fatemeh Rahbarizadeh.
Medical Oncology 2022 Aug; 39(11):177.
Application：Sub, Recombinant proteins.
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False-positive immunogenicity responses are caused by CD20+ B cell membrane fragments in an anti-ofatumumab antibody bridging assay.
Chen K, Page JG, Schwartz AM, Lee TN, Dewall SL, Sikkema DJ, Wang C.
Journal of Immunology 2013 Aug; 394(1-2):22.
Application：Func, Human, B cells, Fibroblastic cells.
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Isolation and characterization of human anti-CD20 single-chain variable fragment (scFv) from a Naive human scFv library.
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