MS4A1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and MS4A1 expressing 293 cells (Green) using MS4A1 purified MaxPab mouse polyclonal antibody.
Western Blot (Tissue lysate)
MS4A1 MaxPab polyclonal antibody. Western Blot analysis of MS4A1 expression in human spleen.
Western Blot (Transfected lysate)
Western Blot analysis of MS4A1 expression in transfected 293T cell line (H00000931-T01) by MS4A1 MaxPab polyclonal antibody.
Lane 1: MS4A1 transfected lysate(32.67 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to MS4A1 on formalin-fixed paraffin-embedded human lymph node. [antibody concentration 3 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MS4A1 protein.
Immunogen
MS4A1 (NP_068769.2, 1 a.a. ~ 297 a.a) full-length human protein.
Sequence
MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and MS4A1 expressing 293 cells (Green) using MS4A1 purified MaxPab mouse polyclonal antibody.Western Blot (Tissue lysate)
MS4A1 MaxPab polyclonal antibody. Western Blot analysis of MS4A1 expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of MS4A1 expression in transfected 293T cell line (H00000931-T01) by MS4A1 MaxPab polyclonal antibody.
Lane 1: MS4A1 transfected lysate(32.67 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to MS4A1 on formalin-fixed paraffin-embedded human lymph node. [antibody concentration 3 ug/ml] -
Gene Info — MS4A1
Entrez GeneID
931GeneBank Accession#
NM_021950.3Protein Accession#
NP_068769.2Gene Name
MS4A1
Gene Alias
B1, Bp35, CD20, LEU-16, MGC3969, MS4A2, S7
Gene Description
membrane-spanning 4-domains, subfamily A, member 1
Omim ID
112210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq
Other Designations
B-lymphocyte cell-surface antigen B1|CD20 antigen|CD20 receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Identification of an alternative CD20 transcript variant in B-cell malignancies coding for a novel protein associated to rituximab resistance.
Henry C, Deschamps M, Rohrlich PS, Pallandre JR, Remy-Martin JP, Callanan M, Traverse-Glehen A, GrandClement C, Garnache-Ottou F, Gressin R, Deconinck E, Salles G, Robinet E, Tiberghien P, Borg C, Ferrand C.
Blood 2010 Mar; 115(12):2420.
Application：IF, WB, Human, HEK 293T cells.
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Identification of an alternative CD20 transcript variant in B-cell malignancies coding for a novel protein associated to rituximab resistance.
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