CD8A polyclonal antibody (A01)
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More Files
- More Functions
Western Blot (Cell lysate)
CD8A polyclonal antibody (A01), Lot # 050912JC01. Western Blot analysis of CD8A expression in Daoy.
Western Blot (Cell lysate)
CD8A polyclonal antibody (A01), Lot # ABNOVA060619QCS1. Western Blot analysis of CD8A expression in SJCRH30.
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CD8A.
Immunogen
CD8A (NP_001759, 22 a.a. ~ 131 a.a) partial recombinant protein with GST tag.
Sequence
SQFRVSPLDRTWNLGETVELKCQVLLSNPTSGCSWLFQPRGAAASPTFLLYLSQNKPKAAEGLDTQRFSGKRLGDTFVLTLSDFRRENEGYYFCSALSNSIMYFSHFVPV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CD8A polyclonal antibody (A01), Lot # 050912JC01. Western Blot analysis of CD8A expression in Daoy.Western Blot (Cell lysate)
CD8A polyclonal antibody (A01), Lot # ABNOVA060619QCS1. Western Blot analysis of CD8A expression in SJCRH30.ELISA
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Gene Info — CD8A
Entrez GeneID
925GeneBank Accession#
NM_001768Protein Accession#
NP_001759Gene Name
CD8A
Gene Alias
CD8, Leu2, MAL, p32
Gene Description
CD8a molecule
Gene Ontology
HyperlinkGene Summary
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD8 antigen alpha polypeptide|CD8 antigen, alpha polypeptide (p32)|Leu2 T-lymphocyte antigen|OKT8 T-cell antigen|T cell co-receptor|T-cell antigen Leu2|T-cell surface glycoprotein CD8 alpha chain|T-lymphocyte differentiation antigen T8/Leu-2|T8 T-cell ant
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Interactome
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Pathway
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