CD247 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
CD247 transfected lysate.
Western Blot
Lane 1: CD247 transfected lysate ( 18.70 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CD247 full-length
Host
Human
Theoretical MW (kDa)
18.7
Interspecies Antigen Sequence
Mouse (81); Rat (85)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CD247 antibody (H00000919-D01P) by Western Blots.
SDS-PAGE Gel
CD247 transfected lysate.
Western Blot
Lane 1: CD247 transfected lysate ( 18.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CD247
Entrez GeneID
919GeneBank Accession#
NM_198053Protein Accession#
NP_932170.1Gene Name
CD247
Gene Alias
CD3-ZETA, CD3H, CD3Q, CD3Z, T3Z, TCRZ
Gene Description
CD247 molecule
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD247 antigen, zeta subunit|CD3Z antigen, zeta polypeptide (TiT3 complex)|OTTHUMP00000032544|T-cell antigen receptor complex, zeta subunit of CD3|T-cell receptor T3 zeta chain|T-cell receptor zeta chain|T-cell surface glycoprotein CD3 zeta chain
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Interactome
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Pathway
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Disease
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