CD1D MaxPab mouse polyclonal antibody (B01)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of CD1D expression in transfected 293T cell line (H00000912-T01) by CD1D MaxPab polyclonal antibody.
Lane 1: CD1D transfected lysate(36.96 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CD1D protein.
Immunogen
CD1D (AAH27926.1, 1 a.a. ~ 335 a.a) full-length human protein.
Sequence
MGCLLFLLLWALLQAWGSAEVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFTSRFKRQTSYQGVL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CD1D expression in transfected 293T cell line (H00000912-T01) by CD1D MaxPab polyclonal antibody.
Lane 1: CD1D transfected lysate(36.96 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CD1D
Entrez GeneID
912GeneBank Accession#
BC027926Protein Accession#
AAH27926Gene Name
CD1D
Gene Alias
CD1A, MGC34622, R3
Gene Description
CD1d molecule
Omim ID
188410Gene Ontology
HyperlinkGene Summary
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. [provided by RefSeq
Other Designations
CD1D antigen|CD1D antigen, d polypeptide|HMC class I antigen-like glycoprotein CD1D|OTTHUMP00000024053|T-cell surface glycoprotein CD1d|differentiation antigen CD1-alpha-3|thymocyte antigen CD1D
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Interactome
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Pathway
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Disease
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Publication Reference
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CD1d-dependent, iNKT-cell cytotoxicity against keratinocytes in allergic contact dermatitis.
Balato A, Zhao Y, Harberts E, Groleau P, Liu J, Fishelevich R, Gaspari AA.
Experimental Dermatology 2012 Dec; 21(12):915.
Application：WB-Tr, Human, Keratinocytes.
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A Central Role for Transcription Factor C/EBP-?] in Regulating CD1d Gene Expression in Human Keratinocytes.
Sikder H, Zhao Y, Balato A, Chapoval A, Fishelevich R, Gade P, Singh IS, Kalvakolanu DV, Johnson PF, Gaspari AA.
The Journal of Immunology 2009 Aug; 183(3):1657.
Application：WB-Tr, Human, Keratinocytes.
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CD1d-dependent, iNKT-cell cytotoxicity against keratinocytes in allergic contact dermatitis.
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