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Last updated: 2016/11/27

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KRIT1 Pre-design Chimera RNAi

  • Catalog # : H00000889-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens KRIT1, ankyrin repeat containing (KRIT1), transcript variant 5, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001013406
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 889
  • Gene Name:
  • KRIT1
  • Gene Alias:
  • CAM,CCM1
  • Gene Description:
  • KRIT1, ankyrin repeat containing
  • Gene Summary:
  • This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
  • Other Designations:
  • ankyrin repeat-containing protein Krit1,cerebral cavernous malformations 1,krev interaction trapped 1
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