CCBL1 monoclonal antibody (M02), clone 1B12
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant CCBL1.
Immunogen
CCBL1 (AAH33685, 1 a.a. ~ 374 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAKQLQARRLDGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAVEAFQHAVSGDFMLNQYTKTFVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIFYSVPHQKHFDHYIRFCFVKDEATLQAMDEKLRKWKVELWP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (71); Rat (72)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (66.88 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CCBL1 expression in transfected 293T cell line by CCBL1 monoclonal antibody (M02), clone 1B12.
Lane 1: CCBL1 transfected lysate(27.4 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CCBL1 is 3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to CCBL1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — CCBL1
Entrez GeneID
883GeneBank Accession#
BC033685Protein Accession#
AAH33685Gene Name
CCBL1
Gene Alias
FLJ95217, GTK, KAT1, KATI, MGC29624
Gene Description
cysteine conjugate-beta lyase, cytoplasmic
Omim ID
600547Gene Ontology
HyperlinkGene Summary
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022311|beta-lysase, kidney|cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)|cytoplasmic cysteine conjugate-beta lyase|glutamine transaminase K|glutamine-phenylpyruvate aminotransferase|kyneure
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Interactome
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