CBR1 monoclonal antibody (M01), clone 4G11-1C7
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CBR1 is approximately 1ng/ml as a capture antibody.
Western Blot detection against Immunogen (56.21 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant CBR1.
Immunogen
CBR1 (AAH02511.1, 1 a.a. ~ 277 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQW
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (56.21 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CBR1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — CBR1
Entrez GeneID
873GeneBank Accession#
BC002511Protein Accession#
AAH02511.1Gene Name
CBR1
Gene Alias
CBR, SDR21C1, hCBR1
Gene Description
carbonyl reductase 1
Omim ID
114830Gene Ontology
HyperlinkGene Summary
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. [provided by RefSeq
Other Designations
carbonyl reductase (NADPH) 1|prostaglandin 9-ketoreductase|prostaglandin-E(2) 9-reductase|short chain dehydrogenase/reductase family 21C, member 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Two non-synonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin.
Bains OS, Karkling MJ, Grigliatti TA, Reid RE, Riggs KW.
Drug Metabolism and Disposition 2009 May; 37(5):1107.
Application：WB-Re, Recombinant protein.
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Two non-synonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin.
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