RUNX3 (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of RUNX3 transfected lysate using rabbit polyclonal anti-RUNX3 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-RUNX3.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74%); Rat (72%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of RUNX3 transfected lysate using rabbit polyclonal anti-RUNX3 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-RUNX3.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-RUNX3 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-RUNX3 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — RUNX3
Entrez GeneID
864Gene Name
RUNX3
Gene Alias
AML2, CBFA3, FLJ34510, MGC16070, PEBP2aC
Gene Description
runt-related transcription factor 3
Omim ID
600210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000003370|OTTHUMP00000003371|PEA2 alpha C|PEBP2 alpha C|acute myeloid leukemia gene 2|core-binding factor, runt domain, alpha subunit 3|polyomavirus enhancer-binding protein 2 alpha C subunit|transcription factor AML2
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Interactome
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Disease
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