CBFA2T3 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CBFA2T3 partial ORF ( NP_005178, 342 a.a. - 439 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
YRLEDIAMAHHFRDAYRHPDPRELRERHRPLVVPGSRQEEVIDHKLTEREWAEEWKHLNNLLNCIMDMVEKTRRSLTVLRRCQEADREELNHWARRYS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (92); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CBFA2T3
Entrez GeneID
863GeneBank Accession#
NM_005187Protein Accession#
NP_005178Gene Name
CBFA2T3
Gene Alias
ETO2, MTG16, MTGR2, ZMYND4
Gene Description
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
Omim ID
603870Gene Ontology
HyperlinkGene Summary
The t(16;21)(q24;q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of this gene. In addition, this gene is a putative breast tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene, and a brefeldin A-sensitive association of RII-alpha protein with one of the isoforms has been demonstrated in the Golgi apparatus. [provided by RefSeq
Other Designations
MTG8-related gene 2|myeloid translocation gene on chromosome 16|zinc finger MYND domain-containing protein 4
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