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Last updated: 2017/6/25

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RUNX2 rabbit monoclonal antibody

  • Catalog # : H00000860-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human RUNX2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human RUNX2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human RUNX2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 860
  • GeneBank Accession#:
  • RUNX2
  • Gene Name:
  • RUNX2
  • Gene Alias:
  • AML3,CBFA1,CCD,CCD1,MGC120022,MGC120023,OSF2,PEA2aA,PEBP2A1,PEBP2A2,PEBP2aA,PEBP2aA1
  • Gene Description:
  • runt-related transcription factor 2
  • Gene Summary:
  • This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq
  • Other Designations:
  • CBF-alpha 1,OTTHUMP00000016533,SL3-3 enhancer factor 1 alpha A subunit,SL3/AKV core-binding factor alpha A subunit,acute myeloid leukemia 3 protein,core-binding factor, runt domain, alpha subunit 1,osteoblast-specific transcription factor 2,polyomavirus e
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