CAV2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CAV2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — CAV2
Entrez GeneID
858GeneBank Accession#
NM_001233.3Protein Accession#
NP_001224.1Gene Name
CAV2
Gene Alias
CAV, MGC12294
Gene Description
caveolin 2
Omim ID
601048Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript. [provided by RefSeq
Other Designations
caveolae protein, 20-kD|caveolin 2 isoform a and b
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Interactome
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Pathway
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Disease
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