CAV2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CAV2 full-length ORF ( NP_001224.1, 1 a.a. - 162 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRCFSSVSLQLSQD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
44.7
Interspecies Antigen Sequence
Mouse (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CAV2
Entrez GeneID
858GeneBank Accession#
NM_001233.3Protein Accession#
NP_001224.1Gene Name
CAV2
Gene Alias
CAV, MGC12294
Gene Description
caveolin 2
Omim ID
601048Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Two transcript variants encoding distinct isoforms have been identified for this gene. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by one transcript. [provided by RefSeq
Other Designations
caveolae protein, 20-kD|caveolin 2 isoform a and b
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Interactome
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Pathway
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Disease
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