CASQ2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CASQ2 partial ORF ( NP_001223, 21 a.a. - 119 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
EGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTPKQFQLKEIVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (89); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CASQ2
Entrez GeneID
845GeneBank Accession#
NM_001232Protein Accession#
NP_001223Gene Name
CASQ2
Gene Alias
FLJ26321, FLJ93514, PDIB2
Gene Description
calsequestrin 2 (cardiac muscle)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq
Other Designations
OTTHUMP00000013749|calsequestrin 2, fast-twitch, cardiac muscle|cardiac calsequestrin 2
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Interactome
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Disease
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