CASP7 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82%); Rat (85%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of CASP7 transfected lysate using rabbit polyclonal anti-CASP7 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CASP7.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-CASP7 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-CASP7 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — CASP7
Entrez GeneID
840Gene Name
CASP7
Gene Alias
CMH-1, ICE-LAP3, MCH3
Gene Description
caspase 7, apoptosis-related cysteine peptidase
Omim ID
601761Gene Ontology
HyperlinkGene Summary
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq
Other Designations
ICE-like apoptotic protease 3|Lice2 alpha/beta/gamma|OTTHUMP00000020510|OTTHUMP00000020511|OTTHUMP00000020512|OTTHUMP00000020514|apoptotic protease MCH-3|caspase 7|caspase 7 isoform delta|caspase 7, apoptosis-related cysteine protease
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Interactome
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Pathway
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Disease
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